I'd check with thadoggfather.
He has tetherme working on his 10.1.1 iPhone.
Roger roger,
so installing and rebooting alone, doesn't do it.
I'd install, reboot. re-JB, then do a re-install in cydia once tethered and substrate enabled, worked for me. should no longer be greyed out
works for me on 7+ 10.1.1 at&t model (Intel radio)
its essentially like a re-install process to get it working every time, post every reboot, etc,
respring, it still retains it I believe,
dev will update it eventually, I'm confident but it works for me
Good info bro.
What version of tetherme you have installed?