200 GB 7200 RPM drives are available now (or are claimed to be available now.) And increases in aerial density also increase raw read/write speed, so a newer, higher-capacity 5400 RPM drive *MAY* be faster than an older 7200 RPM drive. (For example, I have an old 18 GB 10,000 RPM SCSI drive that is noticeably slower than a recent 40 GB 7200 RPM SATA drive.)
I would estimate that this 250 GB 5400 RPM drive could probably handle at least equal read/write speeds to the 100 GB 7200 RPM drive I have in my MacBook Pro. (And I know that the 7200 RPM 60 GB hard drive in my PC laptop benchmarks slower than the 160 GB 5400 RPM hard drive in a friend's PC laptop.)