I thought that Tiger only supported 64 bit command line apps?
Nonetheless, that would make one think that the Blender team would have already put much effort into making a OS X-capable 64-bit build. Hard to see a reason why they wouldn't have.
Grand Central I can understand since Blender is already designed to use multiple threads efficiently, but why would OpenCL not likely be a priority for them? It would likely bring significant performance improvements and, since it's an open spec, would also apply to alternate platforms so long as the driver supports it. And ATI and NVidia are both on board.