After getting some good deals on a 2010 8-core, and a couple of Xeon hex-cores, I went ahead with the upgrade. Basically, I just replaced the two 2.4GHz Quads, with a couple of X5680 chips (3.33GHz, hex). Everything went smoothly, with no issues. I did some Geekbench tests (before & after), with the following results:
(64-bit): My 2010 SP model, with an i7 980x in it ---> 16,100
(64-bit): The 2010 8-core, with the stock 2.4GHz quads ---> 14,807
(64-bit): The machine above, with the upgraded CPUs ---> 27,230
(64-bit): My 2010 SP model, with an i7 980x in it ---> 16,100
(64-bit): The 2010 8-core, with the stock 2.4GHz quads ---> 14,807
(64-bit): The machine above, with the upgraded CPUs ---> 27,230
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