As i'm not supposed to force anyone to using particular software, here's my approach.
In fact, you can do AppleScript with Excel files, if the program's version is up to 2004. Since Excel 2008 doesn't support AppleScript any more, there is no easy way to that. You find a reference
here.
Because of AppleScripting Excel is not easy to handle for the unexperienced Scripter i do often prefer 'preparing' Excel files using 'xls2csv', which is part of the catdoc port. Installing MacPorts via
the MacPort site
and then gettin' catdoc will do the trick.
On the command line, type 'man xls2csv' to see the syntax and how to use, separating the individual sheets in your output.
Properly converted to a CSV, your Script will be able to read in the contents of this file, line-by-line and field-by-field, so you should be able to get out the information needed. I'm not assuming any given 'formatting', but in case the sheets are more or less identical, that's maybe what you want.
As i have no idea how familiar you are with embedding 'external command calls' in AppleScript, i don't know how much further info you'll need ...