Yes I have. I did not ever need two GPUs but I needed the boot screen and so installed my GT120 in slot #2 right above the RX580 in slot #1. I honestly thought a x16 lane PCIe card had to be in a x16 slot, which is false but my incorrect belief led me to create this issue
It worked fine for standard "office/daily" use. Just browsing the web or using apps that are not GPU hungry. First time I played any games, so something that actually needed the GPU, it overheated and shutdown the computer.
Solution was easy, put the GT120 in either slot #3 or #4. No overheating has ever occurred again.