Thanks for the added info.
There are some kinds of events that will attempt to read from any connected/powered drives.
So, I think that the easiest way around this is to unmount, then turn off/disconnect drives that are rarely used.
I have two drives that just sit on my desk. It only takes a few moments to either plug in, or turn on either drive, get at the files that I need (or store some other archives (which I keep in a dedicated folder for those occasional transfers), otherwise, those drives just take up space near my Mac. One is used a couple of times per week. The other, used this morning for the first time this month. One does get intermittent use as a paperweight, so it does serve another purpose
I am sure that I have seen a particular terminal command (?) that will prevent the normal mounting of specific drives, but I don't know how well that works, in the long term. Maybe someone with that knowledge will respond to this thread.