Plenty. Just depends on what features you want. BBEdit, TextMate, NetBeans, Eclipse, etc.
TextMate is cool but is not free. Netbeans and Eclipse look like overkill for scripting languages. Basically I just want autoindent, syntax highlight and maybe autocomplete. Actually I just discovered Komodo, but wonder if there's something else.
Smultron could be ok, but can't figure out if and how autoindent works for Python.
I have heard good things from PC people about SciTe but it seems like there's no Mac port.
ViM, please no, I'd rather prefer using XEmacs at that point. Both editors are ok, and UNIX de-facto standards, but I used them a loooooot of years ago during my first years at University where I learned most of the key combinations, but have removed them from mind, and don't feel like I want to learn them again.