I want to run it on my iPad for possibly no other reason than to get swift playground as my 7 year old is extremely excited to use it. Unfortunately (for him) I use my ipp for work and can't afford any issues with 3rd party apps and just can't take the chance (even though I know you can downgrade). I will at least wait for beta 2 or 3 before considering or even just wait it out for the public beta. He as an original mini (which was my first and only one I bought until the pro) and he has access to my wife's iPad 2 but that iPad is not eligible for iOS 10.
As far as the beta 1 goes, it works much better than I expected it to with minor issues with a few apps that don't really matter in daily life i.e. Facebook seems to have issues from time to time. If you don't use your iPad for work or school I would say that you will have no real issues with the beta, if you use it for anything important just sit patiently.