It's alright, but most of the applications I use the most aren't there at the moment due to licensing, restrictions, etc. Looking at what's on my dock....
-MPlayerX is on the App Store and the new version re-won me over from MPlayer OS X Extended for now.
-iLife, which is on the App Store, but I didn't get it from there
-Pixelmator, which I had before the App Store, but is available on it
-uTorrent, which will probably never be on it
-VMWare Fusion, which isn't on it at the moment as far as I know
-R, which is open source and community-driven, with no central devs, so probably won't end up on it
-iWork, which is on it, but I already had it
-Subler, open source, maybe it'll be there in the future? I'm not sure about the restrictions
-MKVTools, same as above
-Jubler, same as above
-Mail.app, N/A.