The guy in the video isn't particularly articulate, but I don't think he's saying anything that's incorrect. (When he says "you won't have this issue on Windows," I'm not even sure what "issue" he's referring to.)
I'm still not sure exactly what you're asking about "viewing images at 100%."
Here are a few observations in case these relate to what you're wondering:
macOS (and iOS) use unilateral concepts of "pixels" (the smallest image element a hardware display is capable of displaying), and "points" (the abstract concept of what has traditionally been about the size of one pixel). Before display technology reached the era of "Retina" or "HiDPI," one pixel and one point were effectively interchangeable terms. With the first Retina display (on the iPhone 4), so many more hardware pixels could be crammed into so much less physical space that for that device, one "point" was deemed equal to two "pixels" along one dimension. The hardware resolution of the iPhone 4 was 640x960, but for the purpose of developers who were now able to start thinking in "points," the resolution was also considered to be "320x480 @2x". Some of today's iPhones are even denser, achieving an "@3x" working resolution – three pixels per point along one dimension. All of this has enabled display resolution to advance independently without messing up designers' lexicon – no matter the display's native DPI, the Mac's menu bar, for example, will continue to be about 24 "points" tall.
All that said: since it's resultingly possible, those system-level Display settings are available, and they effectively alter macOS's treatment of the relationship between a point and a pixel, so that the entire interface will scale.
I think the way an image editing app like Preview, Photoshop or Pixelmator handles the display of an image is probably up to the app. I'm using my iMac at an "@2x" resolution, and I've opened a few images in Preview. The images open by default at some reasonable-looking size, but when I select "Actual Size" from the View menu, the image is presented so that one of the image's pixels equals one display point. (That is, the image is shown at the same size it would appear natively presented on a traditional "@1x" display.)
I've just opened an image in Pixelmator Pro, and unlike Preview, its version of "100%" seemed to be based on matching image pixels to hardware pixels – the image was presented at half the width and height that Preview had chosen. I'd have to ask Pixelmator Pro to display it at its "200%" for its size to match Preview's size.
I've used this Mac for four years and had never noticed that difference in behaviour until you'd prompted me to check, so I certainly wouldn't consider it an "issue."