I just finished replacing the 320GB internal drive in my late 2010 Mini with a 750GB Seagate Momentus XT. I followed the iFixit online tutorial and the whole thing took maybe 15 minutes. Everything running nice and fast. The Momentus has 8GB of SSD where it keeps your most recent data. Very fast boot and load times. I also added a 1TB Western Digital FireWire 800 drive for Time Machine.