Its not restricted to device issues
Its unlikely that this would really help you, but I use a program for molecular biology called Gene Construction Kit 2.5 (textco.com). I installed it and all appeared well. The next day when I tried to open it (the first time I tried opening it after restarting the computer), it initiated a kernel panic. Every time I try to open the program, it crashes the box.
This is on a brand new 17" MBP (1 GB RAM). I have no peripherals plugged in. The only programs I've installed are: Adobe CS suite, Office 2004, Endnote 9, Core Duo Temp, a few biology/chemistry widgets, and GCK 2.5. The kernel panics are completely associated with opening GCK 2.5.
FWIW, I also had a kernel panic while trying to shut the box down this morning. Apparently unrelated to aything else. I've only had this box 72 hrs.