I'm not a huge fan of wireless keyboards and mice. I find they do not work as well as their wired-via-USB counterparts and wireless mice drain batteries like they're are going out of style.
That being said, they are clutter-free and easily moved. The people at Logitech make good computer accessories but I tend to stay away from wireless mice and keyboards.
This particular combo looks very sleek and seems to be well thought-out in its design. Another of my wireless "pet-peeves" though is the infamous USB wireless receiver. I find they are bulky and unattractive masses that sit on your desk (maybe they have become smaller...maybe).
All-in-all, I'd say 'go for it'. If you want this particular combo, I don't see a reason as to why you should not get it.
What did you think of the new Apple Mouse and Keyboard? Do you definitely not want to get those?