Gotcha, thanks. It was an upgrade not a clean install. I didn't get to send the KPs becasue my machine restarted again. Here's the last one..
Anonymous UUID: 73D0794B-1FC0-1407-5519-40B98AD217B3
Mon May 4 16:04:45 2020
*** Panic Report ***
Panic(CPU 0, time 7965386704511): NMIPI for unresponsive processor: TLB flush timeout, TLB state:0x0
RAX: 0x00001157e0eb0ef2, RBX: 0xffffff8015609578, RCX: 0x0000000000000000, RDX: 0x0000116900000000
RSP: 0xffffff87183b3d08, RBP: 0xffffff87183b3d80, RSI: 0x0000000000000002, RDI: 0xffffff801560b7f8
R8: 0x0000000000000000, R9: 0x000000000001862a, R10: 0x0000000000000005, R11: 0x0000073e9608cab1
R12: 0x0000073f138ea704, R13: 0xffffff80cf624da8, R14: 0xffffff80cf99c5e8, R15: 0xffffff80cf624d68
RFL: 0x0000000000000002, RIP: 0xffffff8014e1d4f9, CS: 0x0000000000000008, SS: 0x0000000000000010
Backtrace (CPU 0), Frame : Return Address
0xffffff87183b3f70 : 0xffffff8014f86d34
0xffffff87183b3fd0 : 0xffffff8014e1e396
0xffffff87183b3d80 : 0x0
0xffffff87183b3e40 : 0x73e960b867f
Unaligned frame
Backtrace terminated-invalid frame pointer 0x1a794305f29e00d3
BSD process name corresponding to current thread: launchservicesd
Mac OS version:
17G66
Kernel version:
Darwin Kernel Version 17.7.0: Thu Jun 21 22:53:14 PDT 2018; root:xnu-4570.71.2~1/RELEASE_X86_64
Kernel UUID: 1AE5ACFD-3B6F-3D74-AD52-31F1430DBC6F
Kernel slide: 0x0000000014c00000
Kernel text base: 0xffffff8014e00000
__HIB text base: 0xffffff8014d00000
System model name: MacPro5,1 (Mac-F221BEC8)
System uptime in nanoseconds: 7965386735434
last loaded kext at 4720769086267: com.getdropbox.dropbox.kext 1.11.0 (addr 0xffffff7f97fb6000, size 49152)
last unloaded kext at 4705125863015: com.expressvpn.splittunnel 3 (addr 0xffffff7f97fb6000, size 16384)
loaded kexts:
com.getdropbox.dropbox.kext 1.11.0
com.motu.driver.pro.audio 2.0.0 82439
com.paceap.kext.pacesupport.snowleopard 5.9.1
com.nvidia.CUDA 1.1.0
com.zerodebug.AudioMuxDriver 3
com.Cycling74.driver.Soundflower 1.6.7
com.apple.filesystems.smbfs 3.2.3
com.apple.driver.AppleTyMCEDriver 1.0.3d2
com.apple.driver.AGPM 110.23.37
com.apple.filesystems.autofs 3.0
com.apple.driver.AppleMikeyHIDDriver 131
com.apple.AGDCPluginDisplayMetrics 3.20.13
com.apple.driver.AppleUpstreamUserClient 3.6.5
com.apple.driver.AppleHV 1
com.apple.driver.AppleMCCSControl 1.5.5
com.apple.iokit.IOUserEthernet 1.0.1
com.apple.driver.AppleHDA 281.52
com.apple.driver.AppleMikeyDriver 281.52
com.apple.GeForce 10.3.2
com.apple.iokit.IOBluetoothSerialManager 6.0.7f10
com.apple.driver.pmtelemetry 1
com.apple.Dont_Steal_Mac_OS_X 7.0.0
com.apple.driver.AppleLPC 3.1
com.apple.driver.AppleOSXWatchdog 1
com.apple.driver.ACPI_SMC_PlatformPlugin 1.0.0
com.apple.driver.AppleIntelSlowAdaptiveClocking 4.0.0
com.apple.driver.AudioAUUC 1.70
com.apple.driver.AppleRAID 5.1.0
com.apple.filesystems.apfs 748.51.0
com.apple.filesystems.hfs.kext 407.50.6
com.apple.AppleFSCompression.AppleFSCompressionTypeDataless 1.0.0d1
com.apple.BootCache 40
com.apple.AppleFSCompression.AppleFSCompressionTypeZlib 1.0.0
com.apple.AppleSystemPolicy 1.0
com.apple.iokit.SCSITaskUserClient 404.30.2
com.apple.driver.AppleFWOHCI 5.5.9
com.apple.driver.Intel82574LEthernet 2.7.2
com.apple.driver.AirPort.Brcm4331 800.21.30
com.apple.driver.AppleAHCIPort 329.50.2
com.apple.driver.AppleRTC 2.0
com.apple.driver.AppleHPET 1.8
com.apple.driver.AppleACPIButtons 6.1
com.apple.driver.AppleSMBIOS 2.1
com.apple.driver.AppleACPIEC 6.1
com.apple.driver.AppleAPIC 1.7
com.apple.driver.AppleIntelCPUPowerManagementClient 220.50.1
com.apple.nke.applicationfirewall 183
com.apple.security.TMSafetyNet 8
com.apple.security.quarantine 3
com.apple.driver.AppleIntelCPUPowerManagement 220.50.1
com.apple.kext.triggers 1.0
com.apple.iokit.IOAVBFamily 680.2
com.apple.plugin.IOgPTPPlugin 680.15
com.apple.iokit.IOEthernetAVBController 1.1.0
com.apple.driver.AppleSSE 1.0
com.apple.driver.DspFuncLib 281.52
com.apple.kext.OSvKernDSPLib 526
com.apple.iokit.IOAcceleratorFamily2 378.26
com.apple.iokit.IOSurface 211.15
com.apple.nvidia.driver.NVDAGK100Hal 10.3.2
com.apple.nvidia.driver.NVDAResman 10.3.2
com.apple.iokit.IOSerialFamily 11
com.apple.driver.AppleSMBusController 1.0.18d1
com.apple.iokit.IONDRVSupport 519.20
com.apple.AppleGPUWrangler 3.20.13
com.apple.AppleGraphicsDeviceControl 3.20.13
com.apple.driver.AppleHDAController 281.52
com.apple.iokit.IOHDAFamily 281.52
com.apple.driver.AppleSMBusPCI 1.0.14d1
com.apple.iokit.IOFireWireIP 2.2.9
com.apple.driver.IOPlatformPluginLegacy 1.0.0
com.apple.driver.IOPlatformPluginFamily 6.0.0d8
com.apple.iokit.IOSlowAdaptiveClockingFamily 1.0.0
com.apple.iokit.IOGraphicsFamily 519.20
com.apple.driver.AppleHIDKeyboard 205
com.apple.driver.usb.IOUSBHostHIDDevice 1.2
com.apple.iokit.BroadcomBluetoothHostControllerUSBTransport 6.0.7f10
com.apple.iokit.IOBluetoothHostControllerUSBTransport 6.0.7f10
com.apple.iokit.IOBluetoothHostControllerTransport 6.0.7f10
com.apple.iokit.IOBluetoothFamily 6.0.7f10
com.apple.iokit.IOAHCIBlockStorage 301.40.2
com.apple.driver.usb.AppleUSBHub 1.2
com.apple.driver.AppleUSBAudio 312.6
com.apple.iokit.IOAudioFamily 206.5
com.apple.vecLib.kext 1.2.0
com.apple.driver.usb.networking 5.0.0
com.apple.driver.usb.AppleUSBHostCompositeDevice 1.2
com.apple.filesystems.hfs.encodings.kext 1
com.apple.iokit.IOSCSIMultimediaCommandsDevice 404.30.2
com.apple.iokit.IOBDStorageFamily 1.8
com.apple.iokit.IODVDStorageFamily 1.8
com.apple.iokit.IOCDStorageFamily 1.8
com.apple.iokit.IOAHCISerialATAPI 267.50.1
com.apple.iokit.IOFireWireFamily 4.7.2
com.apple.iokit.IO80211Family 1200.12.2
com.apple.driver.corecapture 1.0.4
com.apple.driver.usb.AppleUSBXHCIPCI 1.2
com.apple.driver.usb.AppleUSBXHCI 1.2
com.apple.driver.usb.AppleUSBEHCIPCI 1.2
com.apple.iokit.IOAHCIFamily 288
com.apple.driver.usb.AppleUSBUHCIPCI 1.2
com.apple.driver.usb.AppleUSBUHCI 1.2
com.apple.driver.usb.AppleUSBEHCI 1.2
com.apple.driver.usb.AppleUSBHostPacketFilter 1.0
com.apple.iokit.IOUSBFamily 900.4.1
com.apple.driver.AppleUSBHostMergeProperties 1.2
com.apple.driver.AppleEFINVRAM 2.1
com.apple.driver.AppleEFIRuntime 2.1
com.apple.iokit.IOSMBusFamily 1.1
com.apple.iokit.IOHIDFamily 2.0.0
com.apple.security.sandbox 300.0
com.apple.kext.AppleMatch 1.0.0d1
com.apple.driver.DiskImages 480.60.1
com.apple.driver.AppleFDEKeyStore 28.30
com.apple.driver.AppleEffaceableStorage 1.0
com.apple.driver.AppleKeyStore 2
com.apple.driver.AppleUSBTDM 439.70.3
com.apple.driver.AppleMobileFileIntegrity 1.0.5
com.apple.iokit.IOUSBMassStorageDriver 140.70.2
com.apple.iokit.IOSCSIBlockCommandsDevice 404.30.2
com.apple.iokit.IOSCSIArchitectureModelFamily 404.30.2
com.apple.iokit.IOStorageFamily 2.1
com.apple.driver.AppleCredentialManager 1.0
com.apple.driver.KernelRelayHost 1
com.apple.iokit.IOUSBHostFamily 1.2
com.apple.driver.usb.AppleUSBCommon 1.0
com.apple.driver.AppleBusPowerController 1.0
com.apple.driver.AppleSEPManager 1.0.1
com.apple.driver.IOSlaveProcessor 1
com.apple.iokit.IOTimeSyncFamily 680.15
com.apple.iokit.IONetworkingFamily 3.4
com.apple.iokit.IOReportFamily 31
com.apple.driver.AppleACPIPlatform 6.1
com.apple.driver.AppleSMC 3.1.9
com.apple.iokit.IOPCIFamily 2.9
com.apple.iokit.IOACPIFamily 1.4
com.apple.kec.pthread 1
com.apple.kec.Libm 1
com.apple.kec.corecrypto 1.0
panic(cpu 10 caller 0xffffff8014f65421): "TLB invalidation IPI timeout, unresponsive CPU bitmap: 0x1, NMIPI acks: 0x0, now: 0x1, deadline: 7965386701463"@/BuildRoot/Library/Caches/com.apple.xbs/Sources/xnu/xnu-4570.71.2/osfmk/x86_64/pmap.c:2798
Backtrace (CPU 10), Frame : Return Address
0xffffffa765e83790 : 0xffffff8014e6c1c6
0xffffffa765e837e0 : 0xffffff8014f95274
0xffffffa765e83820 : 0xffffff8014f87544
0xffffffa765e83890 : 0xffffff8014e1e1e0
0xffffffa765e838b0 : 0xffffff8014e6bc3c
0xffffffa765e839e0 : 0xffffff8014e6b9fc
0xffffffa765e83a40 : 0xffffff8014f65421
0xffffffa765e83ae0 : 0xffffff8014f6bd74
0xffffffa765e83bc0 : 0xffffff8014f6cd44
0xffffffa765e83c20 : 0xffffff8014ef73ef
0xffffffa765e83d60 : 0xffffff8014e77ac3
0xffffffa765e83dc0 : 0xffffff801538da5d
0xffffffa765e83e10 : 0xffffff80153746b3
0xffffffa765e83e30 : 0xffffff80152f3ed3
0xffffffa765e83ea0 : 0xffffff80152f3b64
0xffffffa765e83f00 : 0xffffff80152f7d84
0xffffffa765e83f40 : 0xffffff8015403968
0xffffffa765e83fa0 : 0xffffff8014e1e9c6
BSD process name corresponding to current thread: mDNSResponder
EOF
Without seeing more, this is likely a "bad install." In anything but a MP I would also suggest memory, but less likely. In your upgrade, was this a clean install to a disk? You could be carrying old login items, extensions, or other things that Sierra tolerated, but that HS will not.
But, a clean install to a blank disk will help you isolate the problem.