At first I was exceptical but
@dosdude1 has a YouTube video with a 2011 17" MacBook pro running Catalina and 16 gb of ram @2133 mhz.
Also. There are some topics on this forum with photos running 2133 mhz ram on 2011 macbooks pro.
There is a
stackexchange discussion addressing much of what you’re asking, though the one person who’s tried running the 2133 in their 2011 MBP has run into stability issues with software and with the handling of additional, external displays. OThers, meanwhile, seem to have reported better stability with the 1600MHz variants.
Personally, I have not had exceptional results when mixing variously-clocked RAM sticks on my Early Intel Macs: I get the aforementioned issue of not POST’ing or running into kernel panic during the boot process. And while I’m aware others can and do run mismatched sticks, with at least one of the sticks being what the system expects (in terms of rated clock speed), my own failures have precluded the desire to mess with it much more (unless someone casually and generously handed me a box of old SO-DIMM sticks to tinker with… which has never happened!).
I mean, sure, it would be nice to run 2133MHz sticks in my late 2011 13-inch MBP (same bus, same overall generation and bus clock speed specs on the logic board, etc., as the 15- and 17-inch variants), but not if it comes at the expense of added instability. A reason I love my MBP is because it (and its early 2011 ancestor I used from 2011 up until earlier this year) is a remarkably stable combination of everything.
This is the video
@dosdude1 uploaded
This one you’ll have to talk to dosdude1 about. I’ve seen the video (and that novel mod, as well as his successful mod of throwing in an Ivy Bridge CPU and PCH on the late 2011 17-inch). Frankly, unless you already have the sticks on hand and are willing to anticipate general instability once you do a swap, then it’s probably not worth your time or money. But if you’re willing to dive in and take the risk, you ought to append your field findings to this thread.
You might better off, say, verifying/assuring that your internal SSD (I presume you have an SSD in there, if not two!) has an onboard DRAM cache, as this will help with I/O performance access for the system and for data you may be reading/writing. I found an uptick in general performance after I migrated my system from a budget SSD (reliable, but budget SSD I got for the early 2011, back in 2019, replacing a smaller, name-brand SSD without a DRAM cache I installed back in 2011!). The budget SSD came without a DRAM cache, but after I replaced it with a WD Red
with a DRAM cache (something like 2GB cache, if memory serves), I’ve not run into a bottleneck for anything in the time since.
Consider it food for thought.