I have a 16 inch 2019 Macbook Pro and because of a lack of external ports besides Thunderbolt, have been using a Hub for peripherals such as a back up HDD and a USB2.0 Apple Air DVD player in the past. After an Upgrade to Monterey 12.01, everything worked just fine, except for the DVD player. The player connects to the Hub, is recognized but an error message asking to connect to a USB port on the Mac. Not possible, because there are no USB ports. Thinking the issue might be with the DVD player, It was successfully checked out on two other Macs with USB ports. Thinking the issue might be with the Hub, I ordered a new one with a dedicated USB 2.0 Port. Same issues. The Systems Report indicates the DVD player is recognized, but that's it. The DVD will no longer load, let alone transfer data to the MacBook Pro. A little bit of digging indicated this is a KNOWN issue by Apple. I hope they address it quickly, because without being able to load data, via a CD or DVD, I have an expensive brick. In the meantime BEWARE of upgrades to Monterey if you use any device that doesn't have a Thunderbolt connector and you wish to connect via a Hub