PDF support is much better on OS X than Windows, so there is most likely a native alternative for your PDF app. What does it do, if you're willing to share...
Also, what do you need IE for? If it's just to access sites that think they only work with IE, some simple UserAgent spoofing can be all you really need.
As suggested above DarWine might be able to run your PDF app if it is really very simple, but AFAIK it can't run IE.
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