I've gotten so used to Command+H for home that even if there was a home button, I'd probably forget about it. On the other hand, I've reprogrammed Caps Lock to be Esc and it's been a nice change for a few things.
Another idea I've seen has been to swap the Globe key to Caps Lock (then it works on both the Smart Keyboards and any random Bluetooth keyboards you paid) and put Esc on the Globe key, as that is specific to Smart Keyboards.