I now have Monterey running successfully on one of my Mac Pros. I'm absolutely delighted with the performance but I have one rather annoying issue. If the machine has been been on for more than a few hours it won't shutdown. Initially it seems to shutdown as normal but then instantly reboots (without intervention). Successive shutdowns result in the same behaviour and a hard reset then becomes the only way to shutdown. I don't think I've ever seen this on a Mac before.