Just tried mine with my macbook and skype. Works great! The quality is better than the built in macbook camera, which has produced awesome results for me on iChat. Although the person I was talking to on skype didn't seem to notice a difference in the transmitted quality, which may be a limitation on Skype or bandwidth. The other thing that was improved was the mic quality. The person said I sounded much much clearer. I'm not surprised since the Sony has 4 pickup mics versus versus one for the macbook.
I would imagine the iChat results would be similar, but who knows. I would be happy to try it out sometime over iChat with anyone, but I just noticed something, iChat doesn't seem to have an option to change the camera source like Skype does.