"I use this monitor fine on a 2009 Mac Pro and Nvidia 750 Ti card I had flashed with an EFI by MVC. Much different setup than you but since you said it happens with your MBP too it sounds like the Mac Pro isn't the culprit anyway."
I suspect you may be right. I did read something (can't for the life of me remember where) about this display using a different method to get the video out, MST maybe? It got me thinking that there's a fundamental difference and that Apple's drivers may be at fault.
"First thing's first. What version of OS X are you running? I believe it needs to be 10.9.3 or later to work with DP1.2."
Up to date on both machines. 10.11.04
"The two remaining suspects are the cable/adapter and the monitor. Hopefully it's the former. I'd suggest getting a true DP->mDP cable rather than using an adapter--just one less point of failure. Monoprice makes some good yet cheap ones."
I'm using a Monoprice 6008 10FT 32AWG Mini DisplayPort to DisplayPort Cable. I'm happy to order something else to just rule out cabling, what's a good alternative?
"If that doesn't help then the issue must be with your monitor. What happens if you turn off your Mac, plug in the cable to the Seiki (leave the Seiki on DP1.2) and turn on the Mac. Does it properly display the boot screen? I think I remember some posts that the nMP didn't display a bootscreen with DP1.2 but that may have been fixed by now. If no bootscreen, do you see the desktop before the screen goes black? If so, what happens if you change the resolution (maybe you could use screen sharing to do that)."
Possibly related: My Mac Pro stopped working last Friday, wouldn't even boot. I suspect the D-500 cards have failed, I wonder if messing about with this damn display pushed it over the edge? It's in the shop for repair. I couldn't manage to get it to display the boot options screen (the one you get to by holding option when booting) over display port. Using the HDMI of the Mac Pro into the HDMI of the Seiki did result in this screen being shown. I seem to recall I couldn't even get the login screen to show, the display only came out of sleep when the desktop was loaded.
"The only other thing I could think of is if your Seiki has different firmware than mine. You can check for that if you bring up the monitor menu, choose Setup->Information. I got mine last November and it's on 20150807 Ver 2.00."
Same here.
"Edit: Something's up because here someone posted about a similar problem
https://discussions.apple.com/thread/6988409?tstart=0. You can likely ignore the advice in there about doing a factory reset on the monitor--I think the only reason it "worked" for the one guy who suggested it is because factory reset sets DP back to 1.1 mode."
I saw that thread, same exact problem but no resolution. I've contacted Seiki support, I hope they can shed some light on this, I'll have to return it if not as I bought the thing to get rid of the lag my 39" Seiki 4k TV had as it was limited to 30Hz. I'm really just trying to figure out if I need a refund or a replacement display. I'll try another cable first though. Thanks for your help.