Just a warning for those who are considering upgrading but like to assign global keyboard shortcuts to App Store apps: Sequoia has intentionally disabled the ability for some modifier keys to be registered in sandboxed apps:
developer.apple.com
That's meant to prevent apps from maliciously key-logging, but definitely hampers the ability to set keyboard shortcuts that don't conflict with other apps.
[macOS Sequoia] Using RegisterEven… | Apple Developer Forums
That's meant to prevent apps from maliciously key-logging, but definitely hampers the ability to set keyboard shortcuts that don't conflict with other apps.