I was just starting to poke around with using profiles on my fleet of 15 MacBooks at the office on 10.8.5 Server. I added a shared printer to be pushed over profile manager and my 10.9 client wouldn't pick it up. It also won't load the profile manager webpage or the user portal, which means now that I've deleted the profile from the client, I can't re-enroll it.
My concern is that if I want to continue to use the profile manager I'll have to update all the clients (plus Server) or stay on 10.8.5. Based on the link above, I'll be waiting a bit for that to happen.