I think the concern of the OP is that going to sleep writes the RAM contents to the SSD, and if you're using 16GB (actually USING 16GB, not configured with) and go to sleep often during the course of the day, the number of erase/write cycles can increase to the point where it will make a noticeable impact on how long the SSD will last.
To me at least, Apple's attitude in this respect seems to be, "don't worry, be happy" (don't sweat the details - we won't tell you anyway - let Parent Apple manage for this for you).
Take a look at the following article:
https://www.lifewire.com/change-mac-sleep-settings-2260804
For the OP, your signature indicates a 2011 Mac Mini. Is this what you're using?
Check to see what your hibernate mode is - if it's 0 (what it should be for the Mini), it shouldn't enter hibernation. Just "regular" sleep shouldn't write the RAM contents to disk, it's hibernation that does so (there's also "safe sleep" but that's considered to be the combination of hibernation and keeping power to the RAM chips).
That being said, on my two Mini's (2012, 2014), both upgraded to High Sierra in the past couple of months, I have a sleepimage file of 2GB. I don't know why this is there since I never enter sleep manually. It may just be some sort of default file since the file dates are about when High Sierra was installed and since the files on the two Mini's are the same size. These files are also protected by SIP - they can't be deleted if you have SIP on. For the Mini, in System Preferences -> Energy Saver, on my 2014 Mini, there is checkbox for "Prevent computer from sleeping automatically when the display is off". On my 2012 Mini, I don't have this check box, but I do have a slider which controls computer sleep. Now, if hibernation is off, it shouldn't write to the sleepimage file anyway, but these options are there.
If you have a laptop, my understanding is that it doesn't go into hibernation immediately. On my 2012 MBP (Sierra), which I close the cover for short periods of time when I'm not using it (if I'm not going to use it for hours, I'll turn it off), it hasn't written the sleepimage file in over a month, so for me, that's acceptable.