I've ben running it day 1 and I would not recommend putting it on any device you use for real work reasons. I messed up since I never had any beta problems over the years and did it with Catalina. Right now I'm trying to figure out what keeps causing the "apsd" aka Push Notification process to bog down my processor. It keeps re-indexing and I've excluded all my cloud and external storages. Last week I was plagued with unexplained crashes and restarts. I have to keep deleting the preferences for Illustrator and Photoshop to use them. My iCloud Drive is perpetually stuck saying it's uploading files it counts down to 5k then it goes back up to uploading 40k. I can't open files that have the "in iCloud" icon, nor preview them. I have to fully download the files to avoid freezing and having to force quit the program that it's being opened in. By far, this has been the most unstable beta I've ran in years. I know I know, it's beta but it shouldn't have been released when the most basic of things break, the glue that actually holds macOS together.