Too Many Fonts, ways to remove them?

[Sparced]

I downloaded a 4gb folder of fonts and installed them into Font Book a few days ago. I've noticed After Effects crashing and Illustator has began to refuse to open.

If I open up Font Book it just hangs with the beach ball. I'm using a Retina MacBook Pro with 16GB of ram and didn't foresee this problem. I can remember having a large number from a similar source on my iMac without a problem.

What other apps could possibly resolve this issue? Or should I dig into the systems folder and go remove them manually.

http://i.imgur.com/BjS1T.png

 

[mrapplegate]

Select All Fonts on the left hand side. Then click one on the first font, and shift click on the last one you want deleted and simply delete them.

 

[Sparced]

Font Book wouldn't respond. I only posted the screenshot as proof that there's that many. I've got work due and couldn't wait any longer for a reply.

Just jumped into the user/system/fonts folder of mountain lion and deleted 33,000 files it had in there and hoped for the best.

So far it looks good. Adobe applications are opening again now.