My thoughts (from another recent thread on the same topic)...
Striped SSDs improve sequential read/write speeds. In fact, internally all SSD's are effectively RAID0 arrays of NAND chips for this reason. However, a lot of desktop I/O is random small transfers which doesn't benefit.
So SSDs in RAID0 certainly doesn't hurt and it might make a difference in reading large photos libraries or in video work, but I wouldn't go out of my way to go this route if you're starting from scratch.
It may make sense if the two smaller drives are cheaper than the single larger one.
Things you give up with RAID0:
- An extra drive bay
- Added risk of data loss due to drive failure
- TRIM does not work on RAID arrays
- Potential lack of portability of your data between different systems