What files are in those folders? I think they are just some temp folders. I think you can delete them.
It begs a simple question. Did you look inside? Great clues can be discovered by peeking
Oops looks like you looked
http://answers.yahoo.com/question/index?qid=20100717112517AAPJ0FH
Do you know what the files are from, what made them show up, and if it is okay to delete them?
The yahoo link doesn't explain any of that and seems more directed to windows than OSX.
They're windows install files with the *.mui file being
File Type Multilingual User Interface File
My guess is the OP was messing around with a windows install cd or something and doesn't remember . But in any case they are safe to delete.