I'm an engineer with a background in cost engineering and forensic analysis, with degrees and experience in civil and industrial engineering and a focus on transportation and structural analysis. And, I have a life...
Excel, to me, is not a "spreadsheet application". Excel, like Photoshop, is an extensible platform that provides a basis of analyzing data with one or multiple toolsets and displaying those analyses in graphical format(s). Excel is a tool, a very powerful tool for analyzing and interpreting data sets - and a tool to be used to display the results in a visual format that others can understand/comprehend. MS's VBA shell is IMO one of Excel's most powerful supplementary tools. Honestly, the macOS version of Excel is a gimped shadow of Excel - most of my productive work is on the WinOS platform version of Excel although that may change in the near future (I won't hold my breath...).
Database apps like Access are data containers, too many users that I've encountered use Excel for a placeholder or data container. I'm not judging, but I see this as a waste of Excel's power.
Examples of what I've used Excel for include mapping transportation/run times of light/heavy rail lines, 5-dimensional flow representations (X/Y/Z +time +location) of fluids or soil, and using Excel's reporting features to show budget status - all of this on the Windows platform since the early 90s but still not practical on the Mac platform today. <rant>Until MS opens up Excel on the Mac to
PowerBI or makes their VBA platform as accessible as the Win OS Excel on macOS will be a great tool for "spreadsheets" and recording "CD collections"...</rant> The Office Store is a nice, but pretty toothless addition to Office - give me power tools on the macOS or I'm sticking with Excel on Windows.