I went all-in by replacing an Intel laptop and mini with an M1 laptop and mini. Only two things really impacted me in a significant way:
1. My scanner no longer worked but that was due to macOS driver support and I knew it was coming. Not Apple's fault at all, just crappy third party support.
2. My USB hub was unreliable af with the M1 Macs, which is "meh whatever". I was using a hub to split four external HDDs, which was a crap solution and I knew it. I replaced the external drives with a NAS four bay solution, which works great. I should have done it ages ago, I was just being cheap.
Most of my dedicated app work is done in the Adobe suite and thankfully, Adobe reacted to Apple Silicon MUCH FASTER than they did the Intel transition in 2006, which was agonizing. My other actual work is done primarily in coding apps, which use so few resources that I honestly didn't even know if they were using Rosetta or not most of the time.
At this point, I suspect most people can transition to Apple Silicon pretty seamlessly, though it may force some legacy hardware upgrades so do your research first.