Some ideas:
1. Download and install GoodReader. You can then get all your important files and documents stored on your iPad and organize them into folders.
2. Download Handbrake and start ripping your DVD collection so as to have all your favorite movies optimized for iPad and ready for viewing at a moment's notice.
3. Similarly, pull all your home video of the family over to digital and use AVCHD Converter to merge scenes and format them for iPad.
4. Get moving on your iTunes Playlists. Build tons of them for every mood and situation. Navigating to Artist or Album isn't the way to go.
5. Learn the joy and convenience of RSS feeds and have your news pushed to you. Set up a Google Reader account, paste in RSS feeds from your favorite newspapers and blogs, then bookmark the Google Reader for Mobile on your iPad.
6. Download an app called AppAdvice which gives great up-to-the-minute information on all things iPad, especially emerging new apps and app reviews.
7. Install Now Playing for iPad, set up your favorite movie theaters and watch some trailers of upcoming releases.
8. Back to GoodReader, if you're into, ahem, "adult" viewing material, password protecting a folder in GoodReader will allow you to carry your favorite videos around and keep them safely away from prying eyes.
BJ