No problem!
................Thunderbolt cable
.........................Thunderbolt Cable
4K Monitor --------------------->2014 iMac 5K <------------------- 4K Monitor
3840x2160
.............................5120x2880
..............................3840x2160
60Hz
.......................................................................................60Hz
I use Display Menu (available at the App Store) to change screen settings. Nice utility.
For Mission Control, I have "Displays have separate spaces" unchecked. My daughter has that checked. For me, it makes one huge monitor that I need to have with X-Plane.
Issues:
Like the others have said, there is a shift when going from one screen to another, but if you set them up with the same resolution, that goes away. I have found that having the side monitors in the 4K mode, and the center monitor in the 2880x1620 works best for me. When I load up X-Plane, it's critical that they're all in the 2560x1440 mode, as that eliminates the screen shift when flying.
The GPU can't handle running 13,000 pixels in X-Plane in the highest resolution. This doesn't mean that it doesn't try, but at 5-6fps, I'll be the last to know if I crash. Running it in the 2560x1440 puts it at about 20fps, and that's good enough for the flight training that I'm doing in a Cessna. If I were flying an SR71 10 feet off the ground, I'd want more fps, so I'd lower the resolution.
The main problem with the mixed resolutions, and it doesn't bother me that much, is when I have an Excel sheet that crosses the monitors. On one part, it's microfiche, and on the main monitor it's easy to read. What I usually do is put the sheet all the way over and full screen it on the one screen.
Good Stuff:
Having pretty much wrap around data. My daughter makes movies, so she has iMovie on one screen (right screen), her game on the center (iMac) screen, and Safari going on the 3rd screen (left one). When I log in, it's pretty much the same thing, except I don't play Animal Jam.
iMac is configuration (red stuff are things that are configurable at purchase):
AMD Radeon R9 M295X:
Chipset Model:
AMD Radeon R9 M295X
Type: GPU
Bus: PCIe
PCIe Lane Width: x16
VRAM (Total):
4096 MB
Vendor: ATI (0x1002)
Device ID: 0x6938
Revision ID: 0x0000
ROM Revision: 113-C773AA-731
EFI Driver Version: 01.00.731
Metal: Supported
Displays:
iMac:
Display Type: Retina LCD
Resolution: 5120 x 2880 Retina
Retina: Yes
Pixel Depth: 32-Bit Color (ARGB8888)
Main Display: Yes
Mirror: Off
Online: Yes
Automatically Adjust Brightness: Yes
Built-In: Yes
M280A1:
Resolution: 3840 x 2160 @ 60 Hz
Pixel Depth: 30-Bit Color (ARGB2101010)
Display Serial Number:
124343243 (Odd... both monitors have the same S/N)
Mirror: Off
Online: Yes
Rotation: Supported
Automatically Adjust Brightness: No
Connection Type: DisplayPort
Television: Yes
M280A1:
Resolution: 3840 x 2160 @ 60 Hz
Pixel Depth: 30-Bit Color (ARGB2101010)
Display Serial Number:
124343243
Mirror: Off
Online: Yes
Rotation: Supported
Automatically Adjust Brightness: No
Connection Type: DisplayPort
Television: Yes
Hope that helps, and believe me, I was like you a year ago... there were arguments on whether it could/couldn't be done, and I asked, and people pointed me to the Apple specs (which said it couldn't be done), but then I remembered my 2008 iMac that Apple said the max is 4GB RAM, but there it is, 10 feet from me with 6GB.
Just loaded up X-Plane, and I need to tweak the settings... It's running at 50fps now!!! (look in upper left corner - oops... looked at picture and the top shelf stand is blocking the fps display):
https://1drv.ms/i/s!AkMp0ax8chb2jngJX8pvg4_jDOD-
If you have any questions, let me know. I like helping people out, and giving objective evidence to my statements.
Jeffy