FPS of 125, 250 and 500 are the "magic" numbers. Maintaining those frame rates will give you 6.66% higher jumping ability. That means that you can jump into areas that otherwise aren't accessible. One trick to help that out is get up against the area you want to jump to (ledge, balcony, roof, second story) and look up at the sky. When you watch the frame rate counter you'll see your fps spike. I don't know why a higher frame rate allows higher jumping -- it's part of the Quake engine physics. A buddy explained the math to me once, but I don't remember the rationale.
That's just jumping into otherwise inaccessible areas. The smoother game play of a higher FPS makes for better mouse tracking. Pointless to have a high resolution mouse if you're only mustering 30 fps. The frame rate will impair accuracy far more that a crappy mouse. Far better to have an adequate frame rate and a high resolution mouse.
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