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From what I've been able to gather this is an NVIDIA driver problem for certain (older) Mac Pro's running multiple video cards under Mountain Lion 10.8.3.

Under ML 10.8.2 there was a 'supplemental update' that cured the problem, unfortunately you can't apply that update under 10.8.3 and there's no word from Apple (nothing unusual there) as to whether they're even looking at this issue under 10.8.3 and/or planning a fix. Worst affected are those with older Mac pro's with older video cards and the kernel panics are most often triggered by Flash (but not always).

In my case I have an early 2008 Mac Pro (3,1) with a 880GT and a GT120 card in it running 3 monitors. Only solution I've seen so far is to either remove one of the video cards or to switch to more modern (Apple supported) video cards. Some people have mentioned that the ATI 5770 seems to work ok and that the card will work in older Mac Pro's even though the Apple website says they're for mid-2010 Mac Pro's only - so you pay your money and take a chance!

Incidentally, installing the latest CUDA driver (March 2013) from NVIDIA doesn't help, what's really needed is for NVIDIA to produce a driver that addresses the specific kernel panic message/problem.

PS. Cleaning the dust off your CPU/GPU is always a good move, but it won't help here :rolleyes:
 
Flash

Exactly happens to me when watching flash videos. i reinstalled my system so many time for a couple of days very frustrating. clean install just to know the cause of the problem. all my crash is flash related including watching flv file on my mac. i thought it's a gpu problem but i can play games without problem.
 
my testimonial

Well I've had my Mac Pro crash a number of times since updating to 10.8.3. It's never done this before. Never had any issues when on 10.8.2 with my 670s.

Mac Pro 4,1
2.93ghz quad
8gb ddr3
dual gtx 670s

Here's the crash report [...CUT...]

Hi Folks!
I'm new to the forum, but I often read it.
I've decided to share my experience with you only now because I didn't have any "big troubles" with my mac pro, until now.
I'll try to be short: I've got the same exact problem I quoted, even with tha same error.
My system is a MacPro 4.1 with several add-ons:
1 gpu nvidia GT120
1 Sonnet esata card
1 raid card Apple
1 expansion unit CUBIX with 2 Quadros (mac version), 1 caldigit raid card (not in use)
2 drobos attached to the sonnet card
1 WD my studio book2 for backups.

I've never had problems until I decided to upgrade to Mountain Lion 10.8.3 (formerly I had got 10.6.8).
With the SAME EXACT CONFIGURATION I've noticed two main problems:
1- When browsing with finder QTKitServer process (it should be a process for the files preview with the quick look) was making CPU to 200% usage (I think I solved this issue resetting the spotlite index and rebuilding it)
2- The system freezes looking at videos and restarts (I do NOT have the automatic restart option chosen... I think that's only for rebooting after an energy loss). This occurs often and quite randomly.
In prime time it happened only with firefox and youtube videos.
Then also with Chrome and both videos and hangouts.
Today I was previewing with the space bar 2 different videos recorded with my iPhone and it creashed both times...
In addition finder is very very unstable: sometimes freezes and the only way I have to solve is to reboot (I've also tried with a little script from the terminal I usually used for some issues in the 10.6.8, but it was useless).
I'm very frustrated and disappointed, I use my mac pro for work!
I don't know what to do. I've thought to extract all my additional card 1 by 1 but it could be a very long process and also I need the nvidia cards to work (I agree with you all... it should be something about nvidia and last Apple update).
I'm thinking about to reinsall all (damn...!"?=#@@!!) but to upgrade only to 10.8.2. Could it be a possible workaround?
Thank you for you patience and sorry if I was too long.

PS: I've upgraded also my macbookpro and, with EXACT SAME PROGRAMS and drivers (sure, not the Nvidia Quadro ones...), I've got no one of those issues...
 
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