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UPDATE:

I found two nanoTECH ExpressCard/34 cards that are guaranteed by the eBay seller to work with Mojave:

USB 3.0: https://www.ebay.com/itm/2-Port-USB...pple-MacBookPro-15-17-OSX-10-8-2/262393441049

eSATA: https://www.ebay.com/itm/Single-Por...r-Apple-MacBook-Pro-3Gbps-Mojave/252167752639

I haven't ordered either of these... but at least there are two a Mojave compatible ExpressCard/34 adapters available which should be faster than my 17" Early 2008 MacBook Pro's FireWire 800 and USB 2.0 ports.
 
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I ended up using a $19.99 Sonnet Tempo edge SATA Pro 6GB ExpressCard/34 in my 17" Early 2008 MacBook Pro running Mojave 10.14.3 using DosDude1's macOS Mojave Patcher.
  • Simple Plug n' Play so this must use native macOS EspressCard/34 drivers... unlike the 2008 "vintage" merax eSATA Xpress dual port ExpressCard/34 which crashed as soon as it was inserted in Mojave
  • Apple System Information shows:
    • Negotiated Link Speed = 1.5 Gigabit... MUCH faster than FireWire 800 (800Mbps) or USB 2.0
    • PCI: ExpressCard: AHCI Controller Link Width = x1 and Link Speed = 2.5 GT/s
  • Works perfectly with 200GB 7,200 rpm Hitachi eSATA hard drive for Time Machine backups
Not sure if a USB 3.0 ExpressCard/34 would be faster in actual use since the hard drives are typically the slowest link, but this works for this "vintage" Early 2008 MacBook Pro.

https://smile.amazon.com/gp/product/B0082FI4US
 
UPDATE:

I found two nanoTECH ExpressCard/34 cards that are guaranteed by the eBay seller to work with Mojave:

USB 3.0: https://www.ebay.com/itm/2-Port-USB...pple-MacBookPro-15-17-OSX-10-8-2/262393441049

eSATA: https://www.ebay.com/itm/Single-Por...r-Apple-MacBook-Pro-3Gbps-Mojave/252167752639

I haven't ordered either of these... but at least there are two a Mojave compatible ExpressCard/34 adapters available which should be faster than my 17" Early 2008 MacBook Pro's FireWire 800 and USB 2.0 ports.

I can confirm this NanoTech ExpressCard|34 works on my 17" 2010 MacBookPro running 10.12.6.
The USB3 with bus powered drives too which my Sonnet card doesn't. So far so good.
 
I can confirm this NanoTech ExpressCard|34 works on my 17" 2010 MacBookPro running 10.12.6.
The USB3 with bus powered drives too which my Sonnet card doesn't. So far so good.

I am using High Sierra (MBP 6,1 - 17" 2010 2.53 i5) my Nanotech USB 3.0 ExpressCard is showing up but only upicking up USB 2 and 1 devices only - no USB 3. Is there anyone that can help with this?

I double checked my USB 3 Hard Drive and it works on the regular USB 2.0 ports on my MBP. Nothing happens when I plug it into the ports on the ExpressCard.

Thanks!
 
I am using High Sierra (MBP 6,1 - 17" 2010 2.53 i5) my Nanotech USB 3.0 ExpressCard is showing up but only upicking up USB 2 and 1 devices only - no USB 3. Is there anyone that can help with this?

I double checked my USB 3 Hard Drive and it works on the regular USB 2.0 ports on my MBP. Nothing happens when I plug it into the ports on the ExpressCard.

Thanks!
How long ago did you buy it? Can you contact the seller? Some of them had various different OS compatibilities but the one I bought worked unto Mojave I seem to remember. If that doesn't work, would installing a generic driver work, I can't remember the name now, but people use them for the other non native USB 3 cards.
 
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