I know what REALBasic is. Despite the OO guff and an expanded library, it's still Basic. Which is ultimately just a matter of taste (Basic = the Rodney Dangerfield of languages), but more importantly, unlike Qt Open Source edition, RealBASIC isn't free (by a long shot).
Actually, the problem with REALbasic isn't the language or even the cost. It's REAL's absolute refusal to release critical bug fixes outside their every 90-day release schedule.
In addition, REALbasic's multi-platform strength is also a weakness. The built-in controls and framework are compromised in favor of the lowest common denominator. While this eases development of simple, database-style applications, creating something that feels truly native on any given platform usually requires a great deal of platform-specific work.