I would say not just "extremely I/O heavy tasks." Even basic media production tasks take a hit if you're going to do them on the fusion drive. I'll give a few real world examples that I encountered in my first 3 weeks of using the latest 2015 3TB Fusion (i7, m395x, 32GB 2133mhz ram):
1. Logic Pro X. When using Apple's default samples, logic runs fine. But once I began using a third-party synth, scrolling while playing back 100% of the time produces an intolerable "cracking" sound. For just 1 track. This is fixed by setting the I/O buffer to 256 samples. However when recording, it's best to have the lowest I/O buffer your system can handle, which means you'll have to switch settings constantly while working. Tolerable? Yes. Ideal? No.
2. Premiere Pro CS6. Basic importing 1 track at 1080p to work on (NOT 4k):
1 track (Keep existing settings): 56 frames dropped within 5 seconds of playback
1 track (Change existing settings): Playback stops within 1 second, not possible to measure # of dropped frames.
Tolerable? No, especially when my 2012 MBpro (256 SSD, i7 2.3ghz, 16gb ram, Nvidia 650 with 1GB VRAM) can easily handle 3 tracks of 1080p playback while dropping only 2-3 frames every 10-20 seconds.