Safari + AdBlock is the fastest option on mac. Too bad Chrome doesn't have an AdBlock solution because it just might be faster than Safari. Most pages waste processing on ads than anything else. You'd be surprised how smoother pages scroll and how faster they load. Not to mention battery power saved not processing all the expensive flash and javascript animations.
For anyone interested, you can find AdBlock for Safari
here.
You must run tell Safari to run in 32-bit mode if you're a Snow Leopard user. Easy instructions are on the linked site.