Set your camera to 1/250 with a good exposure and no blown-out highlights, then set in 4.5 minutes for your 16 stopper! Simple, works every time*!Interesting. I've read professionals talk about reciprocity failure even with digital. Somewhat academic as in practice I make an initial "best guess" exposure and then review the results on the histogram and adjust as needed for subsequent exposures.
* works every time does not work when the light changes severely, or when the sun is setting or rising