FWIW, I'm an academic as well (university professor) and I've been using a Rev A MBA since they came out, originally had an 80GB HDD then switched to a 64GB Runcore. I currently have 26GB free.
I use my MBA for work and giving lectures and it has been perfectly fine. I make a concerted effort to not store superfluous files on it (e.g. work only) and haven't run into any problems with space. I make good use of networked and cloud storage (dropbox) as well.
While YMMV, it is possible to live within the 64GB with a little forethought.
This is pretty much what I wanted to hear. Mine will mostly be used for academic/clinical work - essential applications will be Office or iWorks, probably iPhoto, an RSS reader and Papers (excellent application for storing research articles - like iTunes for PDFs!).
I'm pretty much sold on the 64GB now. Hopefully will return with one later today!