Good point! I’m sure we can add a second screen if the main will no longer calibrate correctly...I'm very sure the processing power will be able to last 10 years. I'm using the 2013 Mac Pro and it's as fast as it is on day 1. But I'm not sure if the screen can last that long though. My monitors usually start to turn yellow in year 4-5 with intensive use, and with some colour calibration they still work, but the screen durability is the main thing to worry about on the iMac.
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Agree the RX Vega 64 will likely be a limitation as time goes by, hoping Apple will improve their EGPU support in time.Well, in seven years Apple will announce the iMac Pro obsolete, and you get no repairs and replacement parts.
(RX Vega 64 with 300 Watt I'm looking at you)
Good luck! Especially for the ones with maxed out iMac Pro.