Figured it out!
FlipControlCenter is one of the tweaks I used to use. Been waiting on that one to update as well because it was also causing my apps not to open - so a post on reddit caught my eye. Apparently some people were having issues with FlipControlCenter and the f.lux flipswitch.
Well, I had that flipswitch installed. So I uninstalled it. Both FlipControlCenter and Activator are now working. So, the culprit is the f.lux flipswitch. Which causes a forehead smack moment, because I did run across some mention of that not working.
BTW, rebooted. With both Activator, FlipControlCenter and all my other tweaks installed it came right up. I'm wondering if the f.lux flipswitch might have been causing some other hangs as well as it's booting as fast as it was stock now.
PS. Looks like that was my big issue. iCleaner Pro also update just fine as well!
Awesome to hear you figured out the offending tweak!
I also have activator, flip control center, and icleaner pro installed