If you're new to Civ and *maybe* coming from Civ IV (and found it too complex), and/or if you're really into today's shooters, then Civ V is probably right up your alley.
If you're a Civ veteran (going back to Civ I and II days) then don't even bother. It's a lot of flash and no substance. It's a broken turn-based war game (1UPT? Really??) masquerading as an empire-building strategy game.
Civ as a series faithful to Civ fundamentals is done. Civ V represents a palpable and definite break with the past, for the worse, in terms of management, strategy, and just plain old logic.
There are probably three choices at this point:
1) Keep playing the previous Civ installments until you die. Really. Their replay value, some with mods, is more or less infinite. The Civ community has done a wonderful job. Check out Civ Fanatics.
2) If you're looking for more Civ, but an even greater challenge, then Europa Universalis (the newest being EU III) is your hookup. EU III, in terms of sheer substantive, meaty strategy, makes Civ look like Pac Man.
3) The Total War series looks like an interesting alternative. I'm drifting toward it thanks to the current situation.
No amount of patches and expansions will fix Civ V. For the simple reason is that 2K Games' entire approach to the series is completely different, and to be honest, pretty messed up.