Well, after having issues with my 2010 Mac Pro and this monitor when using an EVGA 680 (flashed) with Mavericks, I had been experiencing perfect functionality with Yosemite. That is -until- I upgraded to 10.10.2, which seems to break sleep for me regardless of whether I use the web drivers or OS drivers.
Crap. Now if the monitor is allowed to sleep, I cannot wake it and have to do a power cycle.
That doesn't sound like a problem with the monitor, unfortunately. You could disable display sleep on the Mac, I suppose.
I am running Yosemite 10.10.2 on a Mid-2012 Retina MacBook Pro without any difficulties.