The limiting factor is the spinning hard drive, not the USB3 connection. I even installed the Yosemite DP on an external USB3/SSD and it was perfectly fine for booting and using Yosemite.
okay heres a good example.
i think usb 2 and usb 3 is perfectly great for 1 hard disk only per port.
but once you start wanting to put them in a hub forget about it
average hard disk = 3.5 watts
usb 2 = 2.5 watts
usb 3 = 4.5 watts
firewire with thunderbolt adapter = 45 watts
if you want to connect two hard disks to 1 usb port , using a windows machine forget about it. your cheap mr usb man that you got from my coke rewards won't even power the drives. with a mac you might not have to worry about it because of their non standard usb ports
unless you use a powered usb hub. but prepare to do some shopping to find out what power that hub puts out
thats the biggest thing that pisses me off abut usb, is that i can't go to fry's electronics anymore and buy a usb enclosure with its own power supply, because everyone in the world thinks every single person is either using a usb hard disk that is rated for 3.5 watts and only using 1 drive per usb port
all i want to say is its sad that firewire has died. because one firewire port can power 12 hard disks without needing hubs or special self powered enclosures