I'm kind of wondering if this might be caused by wear and tear when shutting down and starting up the Mac. I have two 2008 Mac Pro's with the 2 X 3.2 GHz quad core processors and they've been running practically 24/7/365 since late 2009 without the problems that have been talked about here. They only go down for hardware and software updates that require a shutdown, and when there is a power outage. They both each have their own APC UPS so even for a power outage it's only when it is a long one.