I actually have a 24" 4k (samsung) I use with a 2012 mac mini (via a displaylink 4k adapter). I am not young (45) and find that I can use it at 4k generally but sometimes i find I need to drop it to 1080 (HiDPI) when eyes are tired. I wouldn't really recomend it but I think 27" is a good size. I went 24 as I really don't have the space for a 27.