Become a MacRumors Supporter for $50/year with no ads, ability to filter front page stories, and private forums.
Best solution is to create a custom 200 pound concrete case around your imac, then bolt the two peices together. Also booby trap it so if the concrete ever gets unbolted it sets off a self destruct sequence. That will be sure to deter thieves!!
 
in adition to the steel enforced concrete block
some signs like this around the house
350px-Spring_gun.jpg

and some barb razor wire might deter some thiefs too
 
Best software hands down is Project Prey http://preyproject.com/
Latest version even got Wifi Geolocation.
Amongst other things it takes screenshots of the desktop, iSight capture and the location on Google maps.
It's free!
 
Register on MacRumors! This sidebar will go away, and you'll see fewer ads.