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@andykin29

Can you let me know if you get this working. I was planning to buy 10+ of these with the expectation that the PLX8724 would eliminate the end-user complaints about the ASM2824 (which needs very specific parameters met to avoid screen lock on Macs).

I will say - your issue seems electrical.
 
Hi, I have Mac Pro 3.1, early 2008 machine myself and just purchased this NVME PCIe adapter (https://www.amazon.co.uk/gp/product/B093DJ4NRR/ref=ppx_yo_dt_b_asin_title_o02_s00?ie=UTF8&th=1) and initially plugged in a PCIe slot on the motherboard without knowing what I was doing. The card did not recognise by the system. I researched a little and found out that there are 2 PCIe card of version 1.0 (x4) and 2 PCIe card of version 2.0 (x16). I then changed this PCIe card to slot x16, turned on and it works, I can see the NVME drive and format it. Just to post the answer here so if anyone with the same problem can identify the problem and how to solve the issue, like myself.
 
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Hi, I have Mac Pro 3.1, early 2008 machine myself and just purchased this NVME PCIe adapter (https://www.amazon.co.uk/gp/product/B093DJ4NRR/ref=ppx_yo_dt_b_asin_title_o02_s00?ie=UTF8&th=1) and initially plugged in a PCIe slot on the motherboard without knowing what I was doing. The card did not recognise by the system. I researched a little and found out that there are 2 PCIe card of version 1.0 (x4) and 2 PCIe card of version 2.0 (x16). I then changed this PCIe card to slot x16, turned on and it works, I can see the NVME drive and format it. Just to post the answer here so if anyone with the same problem can identify the problem and how to solve the issue, like myself.
This dual M.2 adapter requires a Intel chipset that have Intel PCIe Lane Partitioning (bifurcation) like Intel 299 or 399. Also, even if you have a Mac that have a chipset that have Intel PCIe Lane Partitioning like 2019 Mac Pro, you need a firmware that provide support for it and no Mac ever supported that.

You can use only one blade since your Mac don't have bifurcation support and it's finicky. Get yourself a known supported M.2 adapter. See the first post of the thread below:

 
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I guess that describes the fact that it didn't work in the x4 slot - seems like it should have if it works in the x16 slot. Maybe the problem is with the NVMe in that case? Well, the x4 slot is only PCIe 1.0 so the NVMe could only work up to 800 MB/s.
@HoangUK what NVMe did you use? If you try a supported M.2 adapter (one that doesn't require bifurcation to be fully supported), let us know if the same NVMe or a different NVMe works in the x4 slot.
 
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